Associate Director, Quantitative Pharmacology
Dyne TherapeuticsWaltham, Massachusetts, United States
Posted August 1, 2025
Full Time
About the Company
Dyne Therapeutics is dedicated to improving the lives of individuals with genetically driven neuromuscular diseases by developing therapeutics targeting muscle and the central nervous system. The company advances clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), while also pursuing preclinical research for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. Dyne's mission is to deliver functional improvement, making a significant impact on affected individuals, families, and communities.
Job Description
The Associate Director, Quantitative Pharmacology and Modeling & Simulation (M&S) is responsible for providing strategies, plans, and deliverables on pharmacology and related quantitative analytics for the advancement of programs across all stages of drug development at Dyne Therapeutics. The role involves applying quantitative modeling, including pharmacometrics, modeling based on first principles, and data mining approaches, in support of objectives and progression of drug development programs.
Requirements
- PhD, PharmD, or equivalent training in Quantitative Pharmacology, Pharmaceutical Sciences, Engineering, Physics, Applied Mathematics, and/or Computational Sciences
- 8+ years of bio/pharmaceutical industry drug development experience in Pharmacology- or Biomarker-related functions
- Strong understanding of Clinical Pharmacology principles, PK/PD modeling and simulation, the drug development process and regulatory guidance
Benefits
- Competitive salary
- Opportunities for growth and development
- Collaborative and dynamic work environment
