Centerline Biomedical

Centerline Biomedical develops the Intraoperative Positioning System (IOPS™), a mobile, GPS-like 3D vascular navigation platform that replaces fluoroscopy during minimally invasive endovascular procedures. By generating real-time, radiation-free 3D anatomical models from standard imaging, the system enhances surgical precision, reduces device-placement errors, lowers the risk of endoleaks, and cuts procedural costs. Rooted in the Cleveland Clinic’s Lerner Research Institute, the multidisciplinary team blends clinical insight, engineering, and software to deliver solutions that improve patient outcomes, streamline workflows, and support predictive analytics and surgical training. Centerline’s culture emphasizes innovation, safety, and collaborative problem-solving, positioning it as a leader in precision healthcare and medical device technology.