Co-op Biology-Oncology

Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins.

Requirements

• Cell culture including sterile technique for mammalian cell lines
• Functional genomics approaches (such as CRISPR KO, siRNA/shRNA KD) to interrogate targets to understand their biological function, especially at scale or in a hypothesis-driven way
• Cellular assays to monitor activity of degrader compounds (such as Western blot, JESS, high-content imaging, HiBiT, NanoBRET)
• Establishing and developing new assays to detect target engagement and small molecule binding to targets in vitro and in cells
• Data analysis and interpretation, as well as presenting data in team meetings.
• Meeting with key stakeholders outside of the project team to devise future experiments for downstream applications

Benefits

• Health insurance
• Retirement plan
• Paid time off
• Life insurance