Senior Laboratory Research Scientist Pharmacologist

We are seeking two Senior Laboratory Research Scientists to join the Chemical Biology Science Technology Platform at the Crick. The Chemical Biology STP collaborates with researchers at the Crick to apply chemistry to explore biological questions, working at the cutting edge of biomedical science in disciplines such as cancer, infectious disease, immunology, neurology, and developmental biology. As an SLRS, you will contribute to establishing state-of-the-art screening approaches for the identification and optimisation of chemical modulators of protein targets.

Requirements

• PhD (or equivalent experience level) in a relevant discipline such as biochemistry, pharmacology or chemical biology.
• Experience of working in a drug discovery environment (in either academia or industry) for at least two years.
• A strong track record of developing and carrying out innovative assay solutions to address chemical biology or medicinal chemistry questions.
• Understanding of theoretical and practical enzymology and/or molecular pharmacology for the characterisation of recombinant targets, combined with a track record of high laboratory productivity.
• Experience and knowledge of in vitro biochemical assay technologies such as time resolved fluorescence resonance energy transfer and fluorescence polarisation.
• Proficiency with a range of data analysis and visualisation tools, such as Graphpad Prism (or Origin, SigmaPlot, Grafit), Dotmatics, Spotfire, Dotmatics Vortex, or equivalent software.

Benefits

• Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.
• Pension Scheme: Defined contribution pension with employer contributions of up to 16%.
• 24/7 GP consultation services.
• Occupational health services and mental health support programs.
• Eye care vouchers and discounted healthcare plans.
• Back-up care for dependents.
• Childcare support allowance.
• Annual leave purchase options.
• Crick Networks offering diverse groups' support, community and inclusive social events.
• Discounted gym memberships, bike-to-work scheme, and shopping discounts.
• Subsidised on-site restaurant and social spaces for team interaction.